Free Seminar – June – Knee Pain Replay

Free Seminar - June - Knee Pain Replay

In this webinar hosted by Dr. Meredith Warner’s clinic, Warner Orthopedics & Wellness, Dr. Warner discussed everything you need to know about knee pain.

There are a variety of things that can result in knee pain. Anything from arthritis, to overuse injury, tendinitis, and more can result in persistent knee pain.

Some knee problems are a result of an injury or overuse. But many knee problems are related to aging and continuous wear and tear. Either way - you can find natural relief that protects the integrity of your joint health.

Make sure to watch our video to hear Dr. Meredith Warner break down the basics of what causes knee pain, as well as help you find natural solutions for improving it.

Find Knee Pain Relief With Well Theory

These Well Theory products are designed by Dr. Meredith Warner herself for your wellness! Each product incorporates powerful, natural ingredients for improving immunity, reducing pain, inflammation, and oxidative stress – and so much more.

This daily Joint Health Multi is formulated by an orthopedic surgeon for natural pain relief, inflammation reduction, and antioxidant-rich support to keep you healthy and active. This unique formulation contains 300mg of anti-inflammatory and pain-relieving PEA.

When combined with turmeric, ginger, and piperine, you get a daily dose of powerful, natural anti-inflammatories with no harmful side effects.

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This collection of vitamins and minerals supports healthy tissues, cartilage, nerves, bones, and joints.

These daily capsules can help fortify your bones, promote collagen formation, and assist in wound healing.

At Well Theory, we strive to give you all the tools you need to take charge of your own health journey. 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
SHOP OUR FULL LINE OF WELLNESS SUPPLEMENTS
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What Is Arnica Gel?

What Is Arnica Gel?

History of Arnica in Medicine

We’ve been using arnica as a medicinal treatment for centuries. Evidence of medicinal practices involving arnica have been observed in North America, Germany, and Russia. 

Arnica starts off as a perennial herbaceous flower that’s native to mountainous regions in Siberia and Central Europe.  It will grow up to two feet tall.  

It’s categorized in the sunflower genus called Asteraceae. Medicinal arnica is usually the species Arnica montana.  If you come across arnica in the wild, you’ll note the resemblance to a sunflower due to its yellow petals and fuzzy center. Today, we can also find arnica in the United States and Canada. 

Its use dates back to the sixteenth century as a treatment option for many different ailments and injuries. 

What Is Arnica Used For?

Arnica can be used in a variety of ways, but it’s most commonly used as a topical solution. 

For any treatment, it’s important to note that arnica must be diluted down. If used in a non-diluted form, arnica can cause illness.  Rarely is arnica used orally.  If it is, it is generally in homeopathic concentrations.  In the US, arnica is allowed as a flavoring ingredient for alcoholic beverages.

It’s been used to treat bruises, sprains, small wounds, aching muscles, joint pain, insect bites, and general swelling or inflammation. In Europe, arnica is regulated as a traditional herbal medicinal product.

There is a study during which subjects received standardized bruises and then applied various topical products. One of those was an arnica product. Dermatologists rated the response of the bruises to the topicals. The others were vitamin K, 1% and 5%, vitamin K and retinol and a placebo. The arnica was clearly superior in reducing bruising against all but a 5% vitamin K ointment. Likewise, in a trial for hand arthritis comparing arnica to topical ibuprofen, the arnica was just as effective for reducing pain.

Its success is due largely to phytochemicals in the plant that provide anti-inflammatory properties. The most notable are helenalin and its derivatives. These are sometimes irritating to some people. Most do not put topical arnica on open wounds either.

And it’s been shown that arnica gel is successful in treating osteoarthritis pain. Its anti-inflammatory and pain relieving properties rival that of ibuprofen and other NSAIDs, but without the harsh side effects.

Finding Relief With Arnica Gel

Dr. Warner created the Well Theory Delta-8 THC Tension + Pain Relief Cream with Arnica Gel to help her patients and others feel the benefits of this powerful natural remedy. 

The unique formulation in our Delta-8 Cream reduces swelling and inflammation associated with osteoarthritis and other pain. 

 

 

It combines the power of Arnica Gel, Menthol, Delta-8, and other skin-soothing ingredients to achieve muscular and joint-pain relief by engaging in the body’s natural inflammatory pathways. 

This cream provides targeted relief to areas where you need it most – without the side effects of NSAIDs, like ibuprofen, that can cause stomach afflictions. 

Check out this topical solution today, and see Arnica Gel in action as it has been for centuries.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
SHOP OUR FULL LINE OF WELLNESS SUPPLEMENTS
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What Type Of Knee Pain Do You Have?

What Type Of Knee Pain Do You Have?

Our knees are one of the most important joints in our body. The knee may experience some of the highest amounts of stress when compared to other joints in the body thus making knee injuries very common. The knee joint is also one of the most complex joints with 4 bones and an extensive network of ligaments and muscles that provide structure and movement.  Also, there are many different nerves that feed the knee and each one can potentially cause pain.

Acute Knee Pain

Acute knee injuries are defined by short-term pain that typically lasts no longer than 3 to 6 months.  Normally, an episode of acute knee pain is one that resolves as tissues heal.  Often, no true source of pain is even found!   There are many structures or reasons that could cause acute knee pain.  Here are a few.  

Fracture – Fractures to the bones that comprise the knee joint are not just painful but also debilitating. These are most typically caused by direct trauma to the knee. Fractures should immediately be seen by a medical professional to prevent further damage and allow for proper healing.  Fractures can happen to the patella, the femur, the tibia or to the fibula.  Also, there are a few times that there is an osteochondral fracture; this is when the surface of the bone where the cartilage lives is damaged.  

Ligament injuries – Ligament tears are very common in sports-related injuries with the most common being MCL (medial collateral ligament) and ACL (anterior cruciate ligament) tears. Ligament injuries will often leave the joint feeling loose and will prevent you from putting any weight on the knee initially.  Most MCL tears will heal on their own with just conservative management.  Although ACL tears usually don’t heal on their own, not everyone needs surgery when they occur.  

Meniscus – The menisci are the cartilage shock absorber pads between the bones that make up the knee joint structure. Injuries to the meniscus usually occur after the knee is twisted.  The menisci are not just important with regard to supporting compressive load.  They also contribute a great deal to the rotational stability of the joint.  

Dislocation – Knee dislocations need immediate medical attention as they can compromise blood flow to the leg and cause other problems if left untreated for an extended period of time.  These are extremely high energy injuries and usually occur with contact sports such as football. 

Condition Related Knee Pain

Several medical conditions can affect the knee and cause pain.

Rheumatoid arthritis – RA is an autoimmune condition that affects joints in the body including the knee. It can cause severe pain and swelling.

Gout – You may be familiar with that gout affects the big toe but it can also affect the knee. Gout pain is caused by a build-up of uric acid crystals that results in intense pain, redness, and warmth in the joint.

Chronic Use & Overuse Pain or degenerative conditions

Patellar tendinitis – This condition occurs when the tendon connecting the kneecap (patella) to the tibia (shin bone) becomes inflamed or painful. This is a chronic condition from repetitive motion, especially in runners and cyclists.  For others, patellar tendinitis will happen naturally just from overall degeneration due to chronic low-grade inflammation and oxidative stress changes in the collagen of the body.  

Osteoarthritis – OA is a condition defined by the wearing down of cartilage in joints due to overuse and/or age. This is the most common form of arthritis and can affect any joint in the body. It most commonly affects the knees and many people seek knee replacement surgery.  OA is a very complicated condition and involves the entire joint structure to include the capsule, ligaments, tendons and internal structures of the knee.  OA is basically a systemic non-communicable chronic condition and is a result of chronic low-grade inflammation and oxidative stress.  While replacement surgery is quite common, there are many other way to mitigate the symptoms of osteoarthritis.  

Prepatellar bursitis – A bursa is fluid-filled sac that reduces friction and cushions pressure points in and around joints. Bursitis occurs when the bursa becomes inflamed.  There are bursal sacs at the hip, the elbow, the shoulder, the ankle and the knee.  The patellar bursa sits on top of the kneecap (patella) and allows for the large flexion and extension movements of the knee joint.  Occasionally this sac will become acutely inflamed and fill with fluid.  Often it also becomes hot and painful.  

INR stands for the International Normalized Ratio. This is a calculation based on a prothrombin time (PT) test that measures how long before a clot starts forming in a blood sample. These tests are performed most commonly on those with abnormal blood clotting and to test the effectiveness of the blood-thinning medication Coumadin (warfarin).

Why Don’t Antioxidants Play Nice With Warfarin?

The main enzyme for processing coumadin is CYP2C9. If a substance inhibits this enzyme (CYP2C9), then it will increase the levels of warfarin in the blood and the opposite is true as well. If you take an herb, eat a plant, eat anything really that changes the activity of that enzyme, it will cause changes in your bleeding times. This is why many physicians choose more modern anticoagulant medication

Ginkgo at a 24% concentration is known to interfere with coumadin. Green tea inhibits CYP2C9 as well. St. John’s wort does as well. Quercetin, scutellarein, baicalein, morin, apigenin, chrysin, and catechin-3-gallate are some more flavonoids that can interact with this enzyme.  Turmeric can have an effect on levels of Coumadin in serum as well.  

This enzyme is affected by oral sulfonylurea hypoglycemics, NSAIDs, COX-2 inhibitors, angiotensin II receptor inhibitors, antidepressants, and antiepileptics as well.

Frequent Blood Tests Are Important

Fortunately, most people on warfarin have blood checks weekly or multiple times per week. If something that you ate or another medication that you took changes the activity of the drug, you will know quickly and be able to modify things.

As you can understand, hundreds of substances could potentially interfere with the CYP2C9 enzyme. You will need to discuss this and your entire diet with your treating physician before taking any health-enhancing substances.  

Natural Supplements That Do Not Effect CYP2C9 Enzyme

Some great supplements that can still be taken while on the blood thinner coumadin include tart cherry extract, omega-3 fatty acids, PEA (palmitoylethanolamide), and resveratrol.  These powerful natural antioxidant supplements do not interact with the CYP2C9 enzyme and should be safe to take in conjunction with coumadin.

Tart Cherry Extract is a great anti-inflammatory that we believe works as well as NSAIDs without all the side effects. It helps reduce inflammation and pain in muscles and joints while fighting off free radicals. 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
SHOP OUR FULL LINE OF WELLNESS SUPPLEMENTS
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June 25, 2022

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June 16, 2022

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Skin Care
Mental Health
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Injur/Rehab
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Parenting
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Elbow
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Easy Exercises to Reduce Inflammation

Easy Exercises to Reduce Inflammation

What Is Inflammation?

Inflammation is natural – it’s a process through which the immune system protects the body and is usually a good thing.  Inflammation that is good is often fast-acting and short-lived.  So, why do we keep hearing that inflammation is so bad?  That is because slow-acting and low-grade chronic inflammation is very bad for human health.  

However, when your body’s inflammatory response continues for long periods of time, it becomes chronic and painful.

Chronic inflammation is linked to several diseases like cancer, heart disease, diabetes, arthritis, and more. Indeed, the group of what is called ‘non-communicable chronic disease’ is thought to be due to the scourge of chronic inflammation.

If you have chronic inflammation, you may experience joint pain and joint or muscle stiffness. These symptoms are a result of irritation caused by swelling of the joint lining and loss of cartilage over periods of time.

Chronic inflammation can also harm internal organs like your heart, lungs, and kidneys. But, you may not experience pain in these areas because you don’t have a lot of nerve endings in these organs.  Obviously, with a heart attack a tumor or infection these organs can have pain.  However, most people are blissfully unaware of the damage happening inside their bodies from inflammation.  Sometimes the only clue is pain brought about by arthritis; this can signify other events happening in other systems in the body. 

You can lower chronic inflammation by quitting smoking and limiting alcohol intake, maintaining a healthy weight, and managing stress. You can also assist in improving your healthy lifestyle with supplements like Dr. Warner’s Tart Cherry Extract and Joint Health Multi with turmeric and ginger.

Regular exercise is also key to inflammation control. 

Easy Exercises To Reduce Inflammation

There are several easy exercises you can do to reduce chronic inflammation. And remember – you don’t have to exercise for hours – just minutes to feel the effects of lowered inflammation. Studies show that 20 minutes of exercise is enough to begin stimulating cells that regulate inflammation.  Many scientists now recommend 3 to 5 episodes of 20-30 minutes of basic movement like walking every week.  

Walking is probably the most accessible exercise to start with. You can start out small with this one. On your next trip to the store, try parking further back in the parking lot and walk that distance. Or maybe incorporate a walk a week into your after-dinner routine.  For example, after Sunday dinner there will be a walk.  Then you can add more post-meal walks as you get more comfortable with that.

Yoga is another great exercise you can do at home – but preferably with the help of a professional yogi who can teach you correct postures and poses. Until you are almost an expert yourself, there is much more benefit to guided yoga  (Dr. Warner’s opinion).  Yoga helps to deeply stretch your fascia and other connective tissue in order to relieve inflammation and stiff muscles; at the same time it will build strength and muscle mass. Finally, the social interaction benefits of a yoga class are quite remarkable.  If you’re already familiar with yoga, you can do this exercise in the comfort of your home by watching tutorials online. 

Swimming is a great low-impact option for relieving inflammation. If you feel a lot of pain or stiffness in your joints as a result of inflammation, swimming can help you overcome that in order to get your exercise in. It also helps improve circulation, which allows for better blood flow, therefore a decrease in inflammation.

Cycling can be a fun way to reduce inflammation while getting outside. It’s also relatively low-impact on your joints and can be a good alternative to swimming if you don’t have access to a pool.  Best, you can set your level of zone intensity as you require with little joint impact also.

While you’re building your exercise routine – it’s also important to nourish your body with the appropriate nutrients that help regulate inflammation. 

That’s why Dr. Warner created several products to help her patients reduce chronic inflammation naturally.

Tart Cherry Extract is a great anti-inflammatory that we believe works as well as NSAIDs without all the side effects. It helps reduce inflammation and pain in muscles and joints while fighting off free radicals. 

You may also consider adding our Joint Health Multi to your daily routine. It contains PEA for pain relief, while turmeric and ginger work together to reduce inflammation and its painful side effects.   Remember, all natural products do not work in the same way as synthetic single molecule drugs.  Their effects will be more subtle and thus more natural.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
SHOP OUR FULL LINE OF WELLNESS SUPPLEMENTS
Recent Posts
June 27, 2022

Free Seminar – June – Knee Pain Replay

June 25, 2022

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June 25, 2022

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June 23, 2022

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June 16, 2022

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June 16, 2022

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Categories
Tags
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Hair Care
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Mental Health
Weight Loss
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Stretches
Workout
Yoga
Allergies
Arthritis
Diabetes
Cancer
Parenting
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Elbow
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Gluten Free
Paleo
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Diets
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Blogs
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June 8, 2022

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Can You Take Natural Supplements While On Coumadin

Can You Take Natural Supplements While On Coumadin

Not everyone’s body is built the same. A significant portion of the population requires the use of blood thinners or anticoagulants to reduce their increased risk of developing risky, life-threatening blood clots. One of the most prescribed anticoagulants is Coumadin (warfarin). Those on anticoagulants like warfarin are trying to maintain their INR. Many herbal antioxidants are also known anticoagulants, that when taken with warfarin can thin the blood beyond the desired effect.

While globally Coumadin is heavily prescribed, in the USA it has been largely supplanted by more specific anti-thrombogenics that do not require weekly blood tests to determine levels.

What Does INR Mean?

INR stands for the International Normalized Ratio. This is a calculation based on a prothrombin time (PT) test that measures how long before a clot starts forming in a blood sample. These tests are performed most commonly on those with abnormal blood clotting and to test the effectiveness of the blood-thinning medication Coumadin (warfarin).

Why Don’t Antioxidants Play Nice With Warfarin?

The main enzyme for processing coumadin is CYP2C9. If a substance inhibits this enzyme (CYP2C9), then it will increase the levels of warfarin in the blood and the opposite is true as well. If you take an herb, eat a plant, eat anything really that changes the activity of that enzyme, it will cause changes in your bleeding times. This is why many physicians choose more modern anticoagulant medication

Ginkgo at a 24% concentration is known to interfere with coumadin. Green tea inhibits CYP2C9 as well. St. John’s wort does as well. Quercetin, scutellarein, baicalein, morin, apigenin, chrysin, and catechin-3-gallate are some more flavonoids that can interact with this enzyme.  Turmeric can have an effect on levels of Coumadin in serum as well.  

This enzyme is affected by oral sulfonylurea hypoglycemics, NSAIDs, COX-2 inhibitors, angiotensin II receptor inhibitors, antidepressants, and antiepileptics as well.

Frequent Blood Tests Are Important

Fortunately, most people on warfarin have blood checks weekly or multiple times per week. If something that you ate or another medication that you took changes the activity of the drug, you will know quickly and be able to modify things.

As you can understand, hundreds of substances could potentially interfere with the CYP2C9 enzyme. You will need to discuss this and your entire diet with your treating physician before taking any health-enhancing substances.  

Natural Supplements That Do Not Effect CYP2C9 Enzyme

Some great supplements that can still be taken while on the blood thinner coumadin include tart cherry extract, omega-3 fatty acids, PEA (palmitoylethanolamide), and resveratrol.  These powerful natural antioxidant supplements do not interact with the CYP2C9 enzyme and should be safe to take in conjunction with coumadin.

Tart Cherry Extract is a great anti-inflammatory that we believe works as well as NSAIDs without all the side effects. It helps reduce inflammation and pain in muscles and joints while fighting off free radicals. 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
SHOP OUR FULL LINE OF WELLNESS SUPPLEMENTS
Recent Posts
June 27, 2022

Free Seminar – June – Knee Pain Replay

June 25, 2022

What Is Arnica Gel?

June 25, 2022

How Cannabinoids Help Release Tight Fascia

June 23, 2022

What Type Of Knee Pain Do You Have?

June 18, 2022

Easy Exercises to Reduce Inflammation

June 16, 2022

Understanding COX-2 Inhibitors And Heart Disease

Categories
Tags
Body Care
Hair Care
Oral Care
Skin Care
Mental Health
Weight Loss
Injur/Rehab
Exercises
Running
Stretches
Workout
Yoga
Allergies
Arthritis
Diabetes
Cancer
Parenting
Pregnancy
Elbow
Knee
Muscular
Orthopedics
Shoulder
Treatments
Spine/Back
Shoulder
Supplements
Foot & Ankle
Low Carb
Gluten Free
Paleo
Vegan
Vegetarian
Diets
Vitamins
Keto
More
Blogs
June 13, 2022

[VIDEO] CoQ10: The Perfect Supplement For Muscle Pain

June 8, 2022

How Cortisol Works – And How CBD Decreases It

Understanding COX-2 Inhibitors And Heart Disease

Understanding COX-2 Inhibitors And Heart Disease

What Are COX-2 Inhibitors

COX-2 Inhibitors are a newer type of NSAID that block the cyclooxygenase-2 enzyme responsible for inflammation and pain responses. Some prescription COX-2 inhibitors include celecoxib (Celebrex), meloxicam (Mobic), and rofecoxib (Vioxx).

While these medications can significantly reduce pain and inflammation they can increase the risk of cardiovascular events, including myocardial infarction and stroke. Vioxx was actually pulled from the market after FDA approval because of this potential risk.

Heart Effects Of COX-2 Inhibitors

COX-2 inhibitors work very strongly by a single molecule-type interaction and can potentially affect the heart. Celebrex and Mobic are still heavily prescribed globally despite that risk. This is due to the potential benefits of the anti-inflammatory effects.

The company that manufactured Vioxx actually removed its product from the U.S. market in 2004 due to the increased risk of cardiovascular events.

However, studies have not shown similar problems with the Cox-2 inhibitors that remain on the market.  That being said, some cardiologists do not recommend that patients take such medications.  

The VIGOR trial (https://www.nejm.org/doi/full/10.1056/nejm200011233432103) that initially described the cardiac effects of the COX-2 inhibitors has some features that should be recalled as well. The doses of Rofecoxib were two times what is normally recommended for RA patients. The Naproxen was at the correct dose. People with RA are more prone to cardiac events, to begin with, and many ask them to take a baby aspirin daily; aspirin was not allowed in this study. The overall absolute risk was still quite low in this trial, although it was higher for Rofecoxib than Naproxen; the rest is history.  

NSAIDS in general and Cox-2 inhibitors are known to increase blood pressure and to interfere with blood pressure medications.  The blockade of the Cox enzymes remove a protective restraint on clot formation and atherogenesis along with an increase in BP.  Most believe the Cox-2 inhibitors increase water retention and increase vasoconstriction. Cox-2 inhibitors reduce the excretion of sodium.   The Cox-2 inhibitors will also reduce rates of repair after injury.  Cox-2 inhibitors reduce the formation of prostacyclin and this leads to more thrombosis and more unstable atherosclerosis.  Cox-2 will also increase the activity of NF-kB to act at the genetic level and this causes damage.  Most flavonoids will reduce activity of this transcription factor.

Are Natural COX-2 Inhibitors Better?

Cyanidin, an anthocyanin found in tart cherry and its extracts does have activity against COX enzymes; these enzymes convert omega-6 fatty acids (arachidonic acid) from cell membranes into prostaglandins. They also interact with other phytochemicals and there are a lot of synergistic and beneficial effects; this is hard to tease out. Anthocyanins regulate many different pathways involved in Cardiovascular Disease (CVD) – COX inhibition is only one of the effects of these phytochemicals. 

https://pubmed.ncbi.nlm.nih.gov/27846846/

Anthocyanins can diminish the overall effectiveness of the cyclooxygenase enzyme as well but also have many more heart-protective aspects. Flavonoids are known to enhance longevity and health and reduce cardiovascular risk. This is one reason why plant-based diets can be so healthy. Studies looking at the cardiovascular effects of anthocyanins have found benefits in LDL oxidation, lipid peroxidation, total antioxidant capacity, and reduced levels of CVD biomarkers. The most common cause of mortality and morbidity from CVD is due to atherosclerosis, in particular, unstable clots. Reducing inflammation of the vessel wall and the instability of the plaquing is beneficial overall. Many believe that controlling the ox-LDL levels will prevent many complications. Flavonoids can provide such protection. Heart tissue is especially prone to damage from oxidative stress and flavonoids are protective from that as well.  Flavonoids like cyanidin also reduce the activity of the NF-kB transcription factor and this too will reduce cellular damage.  

Should You Take A Natural COX-2 Inhibitor?

Assuming that all the risk factors that are very strongly associated with CVD are controlled, such as smoking, obesity, diabetes, genetics, physical inactivity, poor diet, and high levels of bad cholesterol, then tart cherries should not raise the risk of heart disease, but rather be protective. Other sources would include acai, chokeberry, elderberry, strawberry, and so on. Tart cherry extract’s flavonoids and phytochemicals will change the enzyme activity at the same time that a cascade of beneficial and antioxidant effects happens. Of course, we will always defer to a treating physician in this matter.  

In general, yes, anthocyanins can reduce the activity of the COX enzymes, but they also reduce cholesterol, triglycerides, oxLDL, blood pressure, aortic stiffness, and they increase the antioxidant capacity of heart tissue. Many epidemiological studies suggest the use of tart cherries. The complexity here is considerable and again if you are worried it is important to speak with one of your physicians knowledgeable in this matter.  

Tart Cherry Extract is a great anti-inflammatory that we believe works as well as NSAIDs without all the side effects. It helps reduce inflammation and pain in muscles and joints while fighting off free radicals. 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation
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