[VIDEO] Our Best Products For Diabetic Neuropathy Relief

[VIDEO] Our Best Products For Diabetic Neuropathy Relief

Don’t let pain hold you back!

For superior natural diabetic nerve pain relief, take our Nervous System Multi and Alpha-Lipoic Acid supplement together! Together, these powerful supplements relieve damaging oxidative stress, assist in protecting nerve endings from damage and inflammation, and block pain signaling. This is a powerful pairing for your natural diabetic nerve pain routine!

IT’S EASY TO GET STUCK IN OLD WAYS OF LIVING. IT’S TIME TO MAKE ROOM FOR THE NEW WAYS OF HEALING.

Nervous System Multi

Complete Nervous System Support + Pain Relief + Optimized Cell Support

Chronic Inflammation can wreak havoc on your cell membranes causing them to harden. This causes cells to become damaged which can contribute to premature aging. Life and health begins and is maintained at the cell level – so in order to get and feel well…. you have to fix the cells.

Alpha-Lipoic Acid

This daily supplement provides powerful, effective support for diabetic neuropathy pain.

Dr. Meredith Warner loves Alpha-lipoic Acid for those with Peripheral Neuropathy to help the pain, numbness, and tingling stay away naturally!

This helps you ward off harmful inflammation & oxidative stress, which can damage nerves that lead to neuropathic pain.

[VIDEO] Alpha-Lipoic Acid: Natural Relief From Diabetic Nerve Pain

[VIDEO] Alpha-Lipoic Acid: Natural Relief From Diabetic Nerve Pain

Alpha-Lipoic Acid supports your body’s regeneration of glutathione – your primary antioxidant. This supports your body’s daily fight against harmful free radicals and Oxidative Stress. This helps protect nerve endings from damage and assisting them in blocking pain signals from the brain.

Natural relief from diabetic nerve pain and neuropathy is possible! 

IT’S EASY TO GET STUCK IN OLD WAYS OF LIVING. IT’S TIME TO MAKE ROOM FOR THE NEW WAYS OF HEALING.

Universal Antioxidant For Optimal Nerve Health

Alpha-lipoic acid (ALA) is a powerful antioxidant supplement that Dr. Warner recommends for natural, sustainable weight loss.

It supports healthy mitochondrial function, and promotes your body’s production of essential antioxidants, like glutathione, to fight damaging free radicals in the body – naturally reducing neuropathic pain.

Total Nervous System Health Support

This unique formulation combines clinically proven supplements like resveratrol, luteolin, chlorella, essential Omega-3’s and more to give you a natural alternative to heavy neuropathic pain medications.

This formulation helps protect frayed nerve endings while supporting total nervous system health.

Natural Sources Of Resveratrol

Natural Sources Of Resveratrol

What is resveratrol? It is a polyphenol and a phytoalexin. Phytoalexins are made by plants to fight infection and cellular damage from things like UV radiation. 

Resveratrol is a polyphenol non flavonoid compound present in strongly pigmented fruits and vegetables. What does that mean? It is a micronutrient packed with antioxidant abilities and other health benefits like improving digestion, weight management, diabetes, cardiovascular diseases, and neurodegenerative diseases. 

With regard to brain and nerve health, resveratrol increases our levels of brain-derived neurotrophic factor (BDNF). There are several natural sources of resveratrol, and you are most likely already eating them!

What Does Resveratrol Do?

Resveratrol supports mitochondrial health in the brain. But what does that mean? It means that resveratrol “protects mitochondrial function and dynamics,” which can lead to neurodegenerative disease when impaired. 

To learn more about resveratrol’s neuroprotective properties, check out our other blog: Why You Should Be Taking A Resveratrol Supplement

What Are Those Natural Sources?

  • Red grapes – Resveratrol is found in the skin of red grapes. It is also present in red wines and some grape juices.
  • Peanuts – That’s right. They are not just a tasty snack. Peanuts are a natural source of resveratrol, not to mention peanut butter and other peanut products. They have it too!
  • Dark chocolate – You didn’t read that wrong. Dark chocolate is also a source of resveratrol. Who doesn’t want another excuse to take a bit of that decadent piece of chocolate?
  • Blueberries – They are also a source of resveratrol. Blueberries don’t have as much as grapes, but they are still a great, tasty choice.

Nervous System Multivitamin

Our Nervous System Multivitamin unique formulation contains 400mg of resveratrol. 

Dr. Meredith Warner carefully formulated this multivitamin to offer powerful support to the entire nervous system with natural anti-inflammatories and antioxidants.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

How Oxidative Stress Harms Nervous System Health

How Oxidative Stress Harms Nervous System Health

What Is Neurodegeneration?

Neurodegeneration is characterized by the progressive loss of selective neural subtypes in the CNS (central nervous system).

Accumulating evidence shows this is mediated by mitochondrial damage.

The common mechanism for lifestyle and non-communicable chronic diseases (NCDs) is mitochondrial dysfunction.

The Role Mitochondria Play In Nervous System Health

Mitochondria are responsible for energy production in cells; they produce the fuel used by all other cellular processes.

Think of mitochondria as a central processing unit; it takes external nutrient input and then produces energy output. Energy is in the form of ATP (adenosine triphosphate) and they also produce important lipid species and provide metabolic substrates for post-translational modifications for cell signaling by DNA.

Part of the process of the electron transport chain (ETC) which is how mitochondria make energy is a byproduct called ROS (reactive oxygen species). These unpaired electrons or free radicals can damage the mitochondria, mitochondrial DNA and other cellular processes. 

The mitochondria have a system to check the ROS from damaging cells, but it is often overwhelmed due to chronic inflammation and excessive oxidative stress.

The mitochondria create energy from nutrients in the inner mitochondrial membrane. Here in the oxidative phosphorylation chain superoxide is made. 

This is a common ROS in the cell formed at complexes I and III during the ECT. This is formed when an oxygen molecule gains an electron. The superoxide anion is then converted to hydrogen peroxide by superoxide dismutase (SOD); this is an important ROS producing enzyme. 

 

The H2O2 molecule can then become a massively damaging hydroxyl radical; this is highly reactive and causes oxidative damage to everything it touches.

ATP is made from ADP in the mitochondria by ATP synthase; this charges the battery of the cell. ATP is the main form of energy and is able to discharge the energy whenever needed by other cells and cell processes.

2ADT molecules can also be converted to an AMP and and ATP molecule by adenylate kinase; these levels of AMP are monitored by AMPK. If AMPK senses too much AMP, then the cell is under-energized. Likewise, too little AMP means the cell is making too much energy.

Low energy states prompt AMPK to initiate protective functions and longevity functions of the cell.

 

The Importance Of Supporting Healthy Mitochondria:

The brain and nervous system require a massive amount of energy to function, and this energy is provided by mitochondria.

Dysfunctional mitochondria basically can’t adapt to a changing environment. Normally, these organelles inside our cells are able to change according to demand. The demand changes according to the stress applied and environment.

Read More: Why You Should Protect Your Mitochondria – And How To Do It

Neurons are generally very long-lived cells; they do not turn over very fast. This means that neurons accumulate damage over time. 

Mitochondrial failure causes too little energy to be produced and not enough repair and detoxification ability for the brain. 

This ultimately results in neuroinflammation and neurodegeneration.

The mitochondria play a critical role in nerve and neuron function. Cells in the PNS (peripheral nervous system) and CNS rely on mitochondrial integrity. Aberrant mitochondrial quality control plays a large role in degeneration of the nervous system. 

Human cells have developed systems for mitochondrial quality control to protect cells from the overproduction or under-neutralization of reactive oxygen species.

Mitochondrial quality control includes:

  • Proteostasis
  • Biogenesis
  • Dynamics
  • Mitophagy
  • Autophagy

Mitochondrial Dysfunction And Inflammation:

A key cause of inflammatory pathways is failure of mitochondrial biogenesis, or biogenetic failure. In these situations there is an increase in calcium levels in the cytoplasm, there is oxidative stress (from ROS) and there is a decrease in normal mitochondrial DNA.  

Mitochondria undergo fusion and fission on a continual basis.  Fusion allows for more energy production.  Fission allows for the repair or removal of damaged mitochondrial DNA and organelles.  A failure of either will lead to an accumulation of inflammation and ROS within the brain which then damages neurons.   

Mitochondrial fission regulates the release of pro-inflammatory mediators.  It does so through nuclear factor kappa light chain enhancer of activated B cells (NF-kB) and MAPK (mitogen activated protein kinase) signaling.  Chronic activation of microglial (CNS support cells) can contribute to neuronal defection.  

One theory is that the accumulation of mitochondrial ROS activates the NLRP3 inflammasome-dependent pathway that elicits chronic inflammation. The NLRP3 inflammasome complex triggers the production of pro-inflammatory cytokines and induces mitochondrial fragmentation. This impairs energy production and disrupts the CNS cell balance.

While the NLRP3 inflammasome complex is crucial for defense against pathogens, it is also the source of many NCDs (AD, gout, autoinflammatory disease, DM, atherosclerosis). Precise control of the NLRP3 inflammasome pathway is mandatory for the health of the cell.

How To Improve Mitochondrial Health

There are ways to improve the function and quality of mitochondria. Two well-known and studies methods are calorie restriction and exercise. Both methods employ a negative balance in terms of nutrient input and energy output needs. By producing a negative balance, the mitochondria are challenged. A challenged mitochondria will improve its function and abilities. 

The challenged mitochondria is better at biogenesis, energy production and other tasks. The unchallenged mitochondria fragments and fails; this is the heart of the NCD problem.

There is a profound effect on mitochondria by exercise. Sustained strenuous physical exercise can double the mitochondrial contents and activity. It will also increase the coupling of mitochondria and improve efficiency and function. 

One of the ways that enhance function of mitochondria during calorie restriction or exercise is the AMPK (AMP-activated protein kinase) path. AMPK is an energy sensor. This molecule is deacetylated during fasting or exercise by SIRT-1. Deacetylation of AMPK increases its activity. 

AMPK functions to sense energy imbalances in the cell and then to initiate cell protection. When the energy supply is low, the cell and organism will respond by slowing down aging and increasing protection from many age-related problems.

Providing antioxidants also improves mitochondrial function by allowing for excessive levels of ROS to be removed from the organelles and cells. Additionally, anti-inflammatory molecules also improve function by protecting the cell membranes and changing the environment of chronic inflammation to a more healthy one.

Less inflammation means less reactive oxygen species and less oxidative stress.

There must be harmony in the generation of mitochondrial components from the nuclear and mitochondrial genomes. This is achieved by the PPAR-gamma, SIRT1 and AMPK signalling pathway. There must be a balance between mitochondrial fusion and fission.

Fusion is the interconnection and enlargement of mitochondria to produce more energy. Fission is the repair/replace cycle for damaged mitochondria. For example, an abnormal accumulation of autophagy vacuoles from fission is a prominent feature of neurons in AD.

Defective oxidative phosphorylation in the mitochondria leads to excessive amounts of ROS and therefore elevation of oxidative stress. This causes more mitochondrial damage and a negative feedback loop happens. The role of antioxidants and anti-inflammatories is to stop this loop and to remove the unneeded ROS.

Many of our products are designed to help reduce inflammation. In particular, our Nervous System Multi is designed to improve neural health by optimizing mitochondrial function.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

[VIDEO] Nerve Pain? Why You Should Supplement With ALA

[VIDEO] Nerve Pain? Here's Why You Should Supplement With ALA

Our newest supplement, Alpha-Lipoic Acid, offers a range of health benefits.

ALA is considered a “universal antioxidant” due to its water- and fat-solubility. This means that it has the unique ability to travel throughout the body, delivering antioxidant benefits where other antioxidants may not be able to. 

It improves cellular energy by reducing oxidative stress, reduces toxic heavy metal levels in the body, and has been found to improve symptoms in those suffering from diabetic neuropathy.

IT’S EASY TO GET STUCK IN OLD WAYS OF LIVING. IT’S TIME TO MAKE ROOM FOR THE NEW WAYS OF HEALING.

Universal Antioxidant For Optimal Nerve Health

Alpha-lipoic acid (ALA) is a powerful antioxidant supplement.

It supports healthy mitochondrial function, and promotes your body’s production of essential antioxidants, like glutathione, to fight damaging free radicals in the body – naturally reducing neuropathic pain.

Total Nervous System Health Support

This unique formulation combines clinically proven supplements like resveratrol, luteolin, chlorella, essential Omega-3’s and more to give you a natural alternative to heavy neuropathic pain medications.

This formulation helps protect frayed nerve endings while supporting total nervous system health.

Our Best Pairing For Diabetic Neuropathy Relief

Our Best Pairing For Diabetic Neuropathy Relief

Our line of surgeon-designed supplements, multivitamins, and topical creams are all designed to be excellent stand-alone additions to your wellness routine. However, you can mix and match our supplements based on your wellness goals!

Today, we’re going to talk about why you should consider pairing our Nervous System Multi with our Alpha-Lipoic Acid supplement.

Supplements For Diabetes Management Care

In her clinical practice, Dr. Meredith Warner sees patients with diabetes every day. To date, most of the prescription medications available for diabetic care, particularly neuropathy care, have left much to be desired. 

Many prescriptions for neuropathy pain, for example, are actually intended to treat other conditions like epilepsy and have some impact on neuropathy – but can have worrying side effects.

Dr. Warner founded her private practice, Warner Orthopedics & Wellness, Well Theory, and our sister company, The Healing Sole, to help as many people as possible find safe, natural, and effective relief from pain and to improve function as they age optimally. 

Our goal is to give you holistic options to enhance your overall well-being every single day.

These concepts and products are not meant to treat, cure, diagnose or prevent any disease, of course. Rather, they are meant to provide natural, safe, proven and helpful alternatives to improve lives along with your current treatments.

Since she sees so many patients with diabetes complications, she decided to develop our Nervous System Multi and ALA supplement to offer a natural alternative to heavy medications. 

Dr. Warner’s personal experience with countless patients using common prescription medications for neuropathy, sciatic and other nerve-based pains enlightened her to the need for a way to assist the overall health and function of the nerve and brain itself, to include the mitochondria of the nerve.

The Nervous System Multi

Our Nervous System Multi is designed to combat the symptoms of one of the most common diabetes complications – neuropathy. As blood sugar levels fluctuate in those with diabetes, nerve endings can become damaged, leading to neuropathy. 

Over time, the connection between the peripheral nerves and the central control system (brain) also changes and becomes damaged. Something has been needed to prevent this and to help the body in its attempts at repairs.

Diabetic neuropathy most commonly affects the hands and feet in the initial stages. It can cause sharp, burning pain, but it can also cause numbness – which is also a worrisome complication. 

If left unchecked, this can lead to Charcot foot and very serious conditions that may even require amputation. Eventually, diabetic neuropathy causes other problems, such as gastroparesis.

It is important to give your body all the building blocks needed at a cellular level to repair damaged nerves and grow healthy ones.

This multi uses clinically high doses of natural anti-inflammatories and nutraceuticals to support your entire nervous system.

Read More: The Science Behind The Ingredients In Our Nervous System Multi

It protects nerve endings from oxidative damage, helps reduce toxic metals in the body and brain, and boosts mitochondrial (cells) function in the brain for better energy – so your entire nervous system can function at peak capacity.

How It Pairs With Alpha-Lipoic Acid

“My goal is to help people age better, age fitter, and enjoy their old age. We’re all going to get old. You can’t stop that.

Meredith Warner, MD

ALA is what is known as a “universal antioxidant,” meaning that it can target free radicals throughout most cells in your body. It does so by being water- and fat-soluble, so it travels quickly throughout cells to provide antioxidant relief wherever they need it most.

It also stimulates the production of your body’s primary antioxidant, glutathione, for an added antioxidant boost. And because it’s essential for mitochondrial health, taking it as a supplement promotes healthier mitochondrial function – so your cells can work more efficiently without being bogged down by oxidative stress. 

Mitochondrial dysfunction seems to be the root cause of many of our problems; for optimal health and wellness, care of the mitochondria is essential.

Like our Nervous System Multi, ALA provides powerful benefits against neuropathy. However, several clinical trials have also found that ALA may help increase insulin sensitivity and help reduce blood sugar – improving diabetes symptom management overall.

When taken together, this multi and supplement provide optimal relief from your diabetic nerve pain and may help with other diabetes symptoms!

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

The Benefits of Alpha-Lipoic Acid For Diabetes Symptoms

The Benefits of Alpha-Lipoic Acid For Diabetes Symptoms

There are different grades of neuropathy in the diabetic person. Diabetic neuropathy might be a focal syndrome, a distal sensorimotor and/or autonomic syndrome or it might be subclinical and simply show up as an abnormality on neurologic testing. 

Diabetic neuropathy is a major public health problem and should be treated as soon as possible.

About 25% of diabetics will have some type of neuropathy. Distal sensorimotor neuropathy causes a lot of health problems and is the source of foot ulcers and in the worst cases, even amputations.

Osteoarthropathy, poor healing, dry and cracked skin, abnormal nails, ligament instability, tight Achilles tendons and pain. Amputation rates are 15-times more in the diabetics than in the rest of the population.

Almost 20% of diabetics will have neuropathic pain. This dramatically ruins quality of life, sleep and functional abilities. It is very difficult to treat this painful condition well. Most physicians try to achieve better glucose control, reduce risk factors for foot damage and treat the pain with pain medications.

Most of the available medications are inadequate and have significant side effects. The normal group of medications used for neuropathic pain include antidepressants, opioids and anticonvulsants.

Today, physicians are also sometimes able to recommend THC as a remedy.

How Alpha-Lipoic Acid Helps With Diabetic Neuropathy

DIabetic neuropathy is the end-result of chronic low-grade inflammation and oxidative stress. The hyperglycemia and poor blood flow found in diabetics start the problems. 

There is an accumulation of advanced glycation end products (AGE); these bind to receptors on the neurons themselves and cause oxidative stress.

There is poor circulation at the microscopic level that feeds the nerves themselves, this results in hypoxia and nitric oxide inactivation. The AGEs also induce NF-kB (nuclear factor-kappa beta) which further causes oxidative stress.

The hyperglycemia and hypoxia also damage the mitochondria of the nerve cells over time. The oxidation causes lipid peroxidation and cellular destruction.

The increased levels of glucose in the serum of diabetics leads to auto-oxidation and the production of AGEs. This is considered a major cause of the ROS found in the peripheral nerves and other organ tissues

This glycation damages natural antioxidants and therefore, not only are more ROS produced but fewer can be cleared. 

Exogenous (external) sources of antioxidants are often needed to keep these free radicals in check. 

Supplementing with Alpha-Lipoic Acid is a great way to both increase your antioxidant intake and encourage your body to produce its own antioxidants.

Alpha lipoic acid normalizes endoneurial activity of an important functional enzyme (Na-K-ATPase). It also improves the uptake of myo-inositol in the nerve cells. This is generally depleted in the hyperglycemic state. Additionally, alpha lipoic acid increases the glucose uptake and the ability of the cell to produce energy.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

[VIDEO] Our New Multi For Total Nervous System Support

[VIDEO] Our New Multi For Total Nervous System Support

Your nervous system is a vital, intricate part of your biology – touching every cell in your body. It’s responsible for your movement, communication, and pain processing.

This nervous system multi is packed with antioxidant-rich ingredients, like chlorella, resveratrol, and luteolin to protect you from free radical damage.

We paired these ingredients with essential omega-3’s, PEA, a natural pain reliever, and N-acetyl-l-cysteine to enhance antioxidant production, reduce inflammation along nerve endings, and promote the formation of healthy neural pathways.

IT’S EASY TO GET STUCK IN OLD WAYS OF LIVING. IT’S TIME TO MAKE ROOM FOR THE NEW WAYS OF HEALING.

Total Nervous System Health Support

This unique formulation combines clinically proven supplements like resveratrol, luteolin, chlorella, essential Omega-3’s and more to give you a natural alternative to heavy neuropathic pain medications.

This formulation helps protect frayed nerve endings while supporting total nervous system health.

Universal Antioxidant For Optimal Nerve Health

Alpha-lipoic acid (ALA) is a powerful antioxidant supplement.

It supports healthy mitochondrial function, and promotes your body’s production of essential antioxidants, like glutathione, to fight damaging free radicals in the body – naturally reducing neuropathic pain.