The Benefits Of Supplementing With NAC (N-ACETYL CYSTEINE)

The Benefits Of Supplementing With NAC (N-ACETYL CYSTEINE)

N-acetylcysteine (NAC) is an immediate or proximate precursor molecule to the strong antioxidant glutathione. Cysteine, glutamate and glycine likewise lead to glutathione. Glutathione helps to control oxidative stress.

NAC provides extra protection to our brains and bodies by enhancing our natural antioxidant abilities, which is why Dr. Warner included 300mg of NAC in her Well Theory Nervous System Multi!

The Benefits of NAC Supplementation

NAC is used in clinical settings to protect against systemic damage from harsh dyes used in imaging studies. It also protects from some chemotherapy agents. Likewise, it is an antidote for overdose from tylenol.

NAC acts to detoxify our bodies and brains. Glutathione is depleted by toxins that enter the system. NAC provides for restoration of normal levels

NAC supports our internal systems that protect us from stress, infections, inflammatory conditions and heavy oxidative stress; it does so through the antioxidant activities and by enhancing nitric oxide function.

Supplementing with NAC is known to increase levels of glutathione; this is body’s major naturally produced antioxidant. 

Because of its ability to enhance antioxidant production, NAC is highly protective of our cells and cellular function.

Glutathione is composed of three amino acids. These are glutamate, glycine and cysteine. Of the three, cysteine is usually the limiting factor; it has the lowest intracellular levels. During stress stimulation (oxidative stress), limited amounts of cysteine halt production of glutathione. 

This results in excessive free radical formation and thus significant mitochondrial and cellular damage. NAC provides augmented levels of cysteine, helping to balance this process.

NAC And Neurodegenerative Diseases

For neurodegenerative disorders in particular, aging is thought to be the biggest risk factor. For example, Alzheimer’s disease (AD) generally affects only those over 65. The risk of AD doubles every 5 years after the age of 65.

There are difficulties with memory, problem-solving, cognition and memory.

One theory is that whatever causes aging must also cause neurodegeneration. Thus, there is blooming work in the field of anti-aging. Much of this research is centered on how antioxidants are linked to anti-aging benefits.

Genes and interventions that have been shown to enhance longevity in one species are conserved in all others. Also, lifespan-extending genes are protective of neurodegenerative disorders. 

Today, there is exciting work being done in the enhancement of molecular mechanisms of anti-aging.

The Findings Of Anti-Aging Research

“My goal is to help people age better, age fitter, and enjoy their old age. We’re all going to get old. You can’t stop that.

Meredith Warner, MD

Multiple compounds are known to extend lifespan; these same compounds can reduce neurodegeneration. Five of these are metformin, rapamycin, resveratrol, N-Acetylcysteine, and curcumin. These and other molecules not only improve lifespan but also add to the ‘healthspan’ of organisms.

This fits into our goal of living better and more optimally. Vital aging is more important than simply extending life.

What Is IN the multivWhy You Should Take An NAC Supplementitamin?

NAC does not require active transport and easily crosses cell membranes to be available for antioxidant production.

NAC reduces the activity of the NF-kB inflammation pathway. This hyperinflammatory pathway becomes especially active in times of stress and oxidative stress. NAC can suppress the damaging cytokine production that invariably results from the activation of the NF-kB path.

Many believe that neurodegenerative disorders are aging related proteinopathies. They are basically due to a build up of poorly folded proteins that are not repaired. These then lead to oxidative stress. This happens in a low GSH (glutathione) environment.

Many scientists believe that toxicity from bad protein in the brain could be cleaned up with the assistance of NAC, due to its abilities to stimulate production of glutathione.

Not only does NAC act as a free radical scavenger, but it is known to act as a life extender in mammal and invertebrate studies and for breast epithelial stem cells; clinical human findings of longevity have not been completed. 

How To Take NAC

Most oral NAC doses are at a 200-400mg range. Doses of 1200mg are discussed in some studies as well. Many advocate taking 600mg capsules up to three times a day.

All antioxidants have the potential to become pro-oxidant at certain doses, so finding supplements that contain appropriate levels of antioxidants is essential. However, in the setting of chronic inflammation and oxidative stress, this is less relevant. Doses of 1.2g daily would be entering the range of concern.

When Dr. Meredith Warner designed her new Nervous System Multi, she took great care to appropriately measure the doses of its antioxidant ingredients. This multivitamin is one of the only targeted, natural multivitamins for nerve pain and nerve health that exists on the market.

And because it was developed by a surgeon who understands the root cause of neuropathic pain, you can rest assured you’re only getting the appropriate dose of NAC.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

5 Amazing Health Benefits of Chlorella

5 Amazing Health Benefits of Chlorella

Our Nervous System Multi is packed with health-boosting ingredients, like Resveratrol, PEA, essential Omega-3’s, Chlorella, and more.

Each ingredient is designed to help improve overall nervous system health, and together, they help to protect frayed nerve endings, enhance mitochondrial function, boost brain health, and more.

We added chlorella to this formulation for many reasons – here are just 5 of them!

Helps Boost Brain Function

In addition to other essential vitamins, your brain needs vitamin B12 to stay healthy. Chlorella is one of the few plant sources on the planet to provide this active form of B12! B12 usually is found in meat and dairy products, so if you’re vegan or vegetarian, you need to be taking a B12 supplement.

Vitamin B12 deficiency has been associated with memory loss - particularly in older adults. B12 functions to help the body make red blood cells, create new nerve cells, and carry out other essential functions. The average adult should be getting around 2.4 micrograms a day.

B12 can’t be made by the body, so your intake depends entirely on food or supplements.

Chlorella Helps Remove Toxins

Chlorella has been shown to help the body clear out heavy metal toxins. 

A study found that “The aminosulphurates and Chlorella and Fucus species of algae supplementation enhanced detoxification of heavy metals by reducing Hg++, Ag, Sn, and Pb levels in patients with long-term dental amalgam filling and titanium implants.” Chlorella Algae also weakens the effects of heavy metal toxicity on your body, brain and nerves.

From cadmium, to nickel, mercury, and more, chlorella has been shown to increase the rate at which your body removes toxins. 

This is essential for nervous system health, as heavy metals can contribute to oxidative stress.

Reduces Aches and Pains

Chlorella contains a property called “chlorella growth factor” (CGF,) which helps rebuild and heal tissues. This is especially true for nerve tissue damage, which makes it a perfect addition to our Nervous System Multi.

This study indicated that patients with fibromyalgia who took chlorella supplements experienced less pain. 

Boosts Your Energy

Chlorella is a source of essential PUFA (polyunsaturated fatty acids) fatty acids. These fatty acids are essential for healthy mitochondrial function.

This journal found that “…supplementation of fatty acids can affect the inner membrane structure of mitochondria and ATP synthesis efficiency though the incorporation of fatty acid into a mitochondrial cardiolipin.” 

Mitochondria are the energy “batteries” of cells and are essential to their function – and therefore the overall health and function of the organs and systems they’re a part of. Chlorella, in addition to its antioxidant and heavy metal-removing benefits, which also help ensure mitochondrial health, contains these essential fatty acids that can improve mitochondrial function.

This translates into better energy and improved function in many key areas of health and wellness!

Helps You Age Vibrantly

Because chlorella helps to enhance so many key areas of your well-being, this makes it a uniquely powerful anti-aging supplement.

Read More: Chlorella – Your Go-To Anti-Aging Supplement 

The intake of carotenoids, like those in chlorella, help protect against aging and age-related diseases.

The antioxidant activity of the marine polyphenols is also protective of DNA and prevents mutations often associated with cancers.

Overall – a marine seaweed-enriched diet diminishes the risk of neurodegenerative disease and helps protect from cellular damage. This is why we included it in our surgeon-formulated Nervous System Multi!

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

Multivitamins Before Surgery

Why You Should Consider A Multivitamin Before Surgery

Why You need a daily multivitamin

before getting surgery

When you are about to undergo surgery, you are usually given a pre-operation checklist for certain things to do or avoid as you prepare for your procedure. 

This can include things like a round of preemptive antibiotics, not eating certain foods or fasting 12-24 hours before your surgery, etc.

 

It’s important to take your surgeon’s advice while you’re preparing for your surgery. Not only are surgeons skilled enough to understand the science behind these procedures, they are also experts in the science behind healing. Nutrition is a key factor in repairing tissues affected by surgery, and starting a supplement regimen is a great way to make sure your body is optimized and ready to begin the healing process.

healing after surgery

and getting back to normal

The healing process after your surgery centers on the building of collagen – which is the main component in many tissues, such as your skin, tendons, muscles, ligaments, cartilage, blood vessels, bone, and more. 

Basically, any tissue that can be affected by surgery – “surgically traumatized tissue” – needs collagen to rebuild. The production of collagen, and the overall healing process, happens in three stages after surgery:

  • Inflammatory phase (up to 5 days): Right after surgery, the body forms a blood clot to stop bleeding. Infection-fighting cells and debris-cleaning cells are sent to the surgical site. Redness, swelling, and inflammation ensues.
  • Proliferative phase (2 days – 3 weeks): Fibroblasts, specialized collagen-forming cells, start building tissue at the surgical site.
  • Remodeling phase (3 weeks – beyond): Over time, the body slowly replaces the collagen that was initially formed at the surgical site with stronger collagen – to strengthen the tissue at the surgical site and promote better function over time.

Without proper nutrition, this healing process can take longer and may even encounter complications. A balanced diet, including essential vitamins and minerals, is extremely important for your healing experience to go smoothly. This is why many surgeons will recommend a multivitamin or specialized supplement regimen before and after surgery.

The right amount and combination of supplements can greatly impact your surgical recovery in a positive way. But you shouldn’t start a supplement regimen without guidance.

Inform (And ask!) Your doctor

about supplements

While most supplements should be safe and beneficial to take as you’re preparing for surgery, there are some supplements that could actually harm your recovery process. 

For example, certain herbal supplements and over-the-counter drugs can reduce your body’s ability to clot blood – an essential component of a smooth recovery. Other supplements can interact negatively with other medications your surgeon may recommend for your healing process.

Your doctor would be more than happy to recommend certain vitamins and minerals to promote healing, and can tell you which supplements to avoid or discontinue while leading up to surgery. You should bring up supplements during your pre-op consultation to make sure there are no delays, as it can take a week or more for any medications to fully leave your system.

For tips on post-surgery recovery, read our blog about why active physical therapy is often a better choice for recovery than bed rest: Recovery And Rehabilitation.

Surgeon-Designed Multivitamin

for your peace of mind

If your doctor prescribes many different vitamins and minerals, your pre- and post-op supplement routine can get expensive, and complicated, very quickly. It’s far easier to carefully choose an inclusive multivitamin and have your doctor confirm that none of the ingredients would interfere with your procedure.

In her years of practice, orthopedic surgeon Dr. Meredith Warner found herself prescribing many different supplements and multivitamins to help her patients prepare for surgery. She specializes in surgical procedures impacting the foot – which contains nearly one-fourth of all bones in the human body. The foot is a complex, flexible structure that contains bones, joints, and more than 100 muscles, tendons and ligaments… all working together to enable movement and balance.

For procedures as high-stakes as these, she believes that proper preparation is essential for ideal outcomes for her patients. 

This is why she created a multi to support the connective tissue in your body. 

It contains highly fortified ingredients ideal for pre- and post-surgery recovery, including Calcium Citrate, Magnesium Oxide, Full Spectrum Hemp Powder, Vitamin C (ascorbic acid),Vitamin D3 (cholecalciferol), Zinc Gluconate, and more.

CBD Vitamin + Multivitamin by Well Theory

One convenient daily serving has everything she recommends her patients take daily to promote surgical recovery and overall musculoskeletal health. Gain peace of mind before your procedure by using our breakthrough formulation that was completely designed for orthopedic conditions.

More Details About Dr. Warner's

custom-designed connective tissue vitamin

These ingredients work best together – while each is a necessary supplement on its own, together they pack a powerful punch.

Full Spectrum Hemp Powder

Hemp interacts naturally with your endocannabinoid system to add a long-lasting anti-inflammatory, tons of antioxidants, and a pain-relieving component.

Vitamin C

Vitamin C promotes proper collagen formation and helps with wound healing, supports the joints, and contributes to healthy bones & teeth.

Calcium Citrate

Calcium Citrate helps promote healthy bone growth, and is integral to nerve signaling & muscle contractions.

Vitamin D3

Vitamin D3 aids in your body’s ability to absorb calcium and supports nerve health. Important to almost every human system.

Magnesium Oxide

Magnesium Oxide also regulates magnesium levels to reduce muscle cramps, fortifies the bones, and is essential for nerve and muscle function.

Zinc Gluconate

Zinc Gluconate is an awesome assistant for wound healing and connective tissue - and also promotes tissue growth and development.

Promoting balance + health at a cellular level is key to maintaining function for many years to come, and recovering from any procedures you may need in the future. 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

Resveratrol & Brain Health

Resveratrol & Brain Health

Our Nerve Health Multi was designed with key ingredients like Luteolin, Omega-3’s, Chlorella, and more to support all elements of neural tissue health.

This multi only includes ingredients shown to assist in protecting frayed nerves and protecting them from future damage, while providing antioxidant benefits to the whole nervous system as well.

One of the ingredients in this multi is resveratrol. Today, we’re going to look at its overall benefits for nervous system health – and focus on its brain health benefits as well!

What Is Resveratrol?

Resveratrol is an antioxidant that is found naturally in red wine and foods like chocolate, peanuts, japanese knotweed and grapes. For plants, resveratrol functions to fight infection, UV radiation damage, stress and injury.

These benefits, like most phytochemical benefits, translate well to the human condition. In addition to its antioxidant benefits, it also may activate sirtuins -which are proteins that are associated with better oxidative metabolism and increased mitochondrial function.

One study found that “Low-to-moderate red wine consumption appeared to reduce age-related neurological disorders including macular degeneration, stroke, and cognitive deficits with or without dementia. Resveratrol has been considered as one of the key ingredients responsible for the preventive action of red wine since the stilbene displays a neuroprotective action in various models of toxicity.” 

Red wine can have health benefits when used in moderation. But since the main compound responsible for its benefits, resveratrol, can be isolated and taken as a nutritional supplement, you can experience red wine’s benefits without any of its side effects.

Resveratrol is a stilbene. Stilbenes are known to possess antitumor, anticarcinogenic and antioxidative properties. In Japan, Itadori tea is used as medicine. Itadori tea is a great source of resveratrol. Itadori tea is brewed with young knotweed shoots.

Resveratrol Benefits For Brain Health

Its antioxidant benefits impact all areas of the nervous system, which includes brain health! But resveratrol has other benefits that directly impact brain function as well.

One study found that “In humans, clinical evidence derived from randomized clinical trials suggests that resveratrol is able to improve cerebral blood flow, cerebral vasodilator responsiveness to hypercapnia, some cognitive tests, perceived performances, and the Aβ40 plasma and cerebrospinal fluid level.” 

As we age, our cognitive health naturally begins to decline. This has been thought inevitable – but you can slow the progression with changes in diet, improvements in your lifestyle, and by adding certain supplements to your routines. Most of ‘aging’ is simply a lack of control of oxidative stress in our opinion.

The same study concluded that “…long-term treatment with adequate dosages of resveratrol with improved bioavailability could exert clinically significant protective effects against cognitive decline in humans.”

Aging and its effects are sometimes considered inevitable. But with the right lifestyle changes, you can maintain your mobility and prolong your cognitive health well into your golden years! 

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

How Oxidative Stress Harms Nervous System Health

How Oxidative Stress Harms Nervous System Health

What Is Neurodegeneration?

Neurodegeneration is characterized by the progressive loss of selective neural subtypes in the CNS (central nervous system).

Accumulating evidence shows this is mediated by mitochondrial damage.

The common mechanism for lifestyle and non-communicable chronic diseases (NCDs) is mitochondrial dysfunction.

The Role Mitochondria Play In Nervous System Health

Mitochondria are responsible for energy production in cells; they produce the fuel used by all other cellular processes.

Think of mitochondria as a central processing unit; it takes external nutrient input and then produces energy output. Energy is in the form of ATP (adenosine triphosphate) and they also produce important lipid species and provide metabolic substrates for post-translational modifications for cell signaling by DNA.

Part of the process of the electron transport chain (ETC) which is how mitochondria make energy is a byproduct called ROS (reactive oxygen species). These unpaired electrons or free radicals can damage the mitochondria, mitochondrial DNA and other cellular processes. 

The mitochondria have a system to check the ROS from damaging cells, but it is often overwhelmed due to chronic inflammation and excessive oxidative stress.

The mitochondria create energy from nutrients in the inner mitochondrial membrane. Here in the oxidative phosphorylation chain superoxide is made. 

This is a common ROS in the cell formed at complexes I and III during the ECT. This is formed when an oxygen molecule gains an electron. The superoxide anion is then converted to hydrogen peroxide by superoxide dismutase (SOD); this is an important ROS producing enzyme. 

 

The H2O2 molecule can then become a massively damaging hydroxyl radical; this is highly reactive and causes oxidative damage to everything it touches.

ATP is made from ADP in the mitochondria by ATP synthase; this charges the battery of the cell. ATP is the main form of energy and is able to discharge the energy whenever needed by other cells and cell processes.

2ADT molecules can also be converted to an AMP and and ATP molecule by adenylate kinase; these levels of AMP are monitored by AMPK. If AMPK senses too much AMP, then the cell is under-energized. Likewise, too little AMP means the cell is making too much energy.

Low energy states prompt AMPK to initiate protective functions and longevity functions of the cell.

 

The Importance Of Supporting Healthy Mitochondria:

The brain and nervous system require a massive amount of energy to function, and this energy is provided by mitochondria.

Dysfunctional mitochondria basically can’t adapt to a changing environment. Normally, these organelles inside our cells are able to change according to demand. The demand changes according to the stress applied and environment.

Read More: Why You Should Protect Your Mitochondria – And How To Do It

Neurons are generally very long-lived cells; they do not turn over very fast. This means that neurons accumulate damage over time. 

Mitochondrial failure causes too little energy to be produced and not enough repair and detoxification ability for the brain. 

This ultimately results in neuroinflammation and neurodegeneration.

The mitochondria play a critical role in nerve and neuron function. Cells in the PNS (peripheral nervous system) and CNS rely on mitochondrial integrity. Aberrant mitochondrial quality control plays a large role in degeneration of the nervous system. 

Human cells have developed systems for mitochondrial quality control to protect cells from the overproduction or under-neutralization of reactive oxygen species.

Mitochondrial quality control includes:

  • Proteostasis
  • Biogenesis
  • Dynamics
  • Mitophagy
  • Autophagy

Mitochondrial Dysfunction And Inflammation:

A key cause of inflammatory pathways is failure of mitochondrial biogenesis, or biogenetic failure. In these situations there is an increase in calcium levels in the cytoplasm, there is oxidative stress (from ROS) and there is a decrease in normal mitochondrial DNA.  

Mitochondria undergo fusion and fission on a continual basis.  Fusion allows for more energy production.  Fission allows for the repair or removal of damaged mitochondrial DNA and organelles.  A failure of either will lead to an accumulation of inflammation and ROS within the brain which then damages neurons.   

Mitochondrial fission regulates the release of pro-inflammatory mediators.  It does so through nuclear factor kappa light chain enhancer of activated B cells (NF-kB) and MAPK (mitogen activated protein kinase) signaling.  Chronic activation of microglial (CNS support cells) can contribute to neuronal defection.  

One theory is that the accumulation of mitochondrial ROS activates the NLRP3 inflammasome-dependent pathway that elicits chronic inflammation. The NLRP3 inflammasome complex triggers the production of pro-inflammatory cytokines and induces mitochondrial fragmentation. This impairs energy production and disrupts the CNS cell balance.

While the NLRP3 inflammasome complex is crucial for defense against pathogens, it is also the source of many NCDs (AD, gout, autoinflammatory disease, DM, atherosclerosis). Precise control of the NLRP3 inflammasome pathway is mandatory for the health of the cell.

How To Improve Mitochondrial Health

There are ways to improve the function and quality of mitochondria. Two well-known and studies methods are calorie restriction and exercise. Both methods employ a negative balance in terms of nutrient input and energy output needs. By producing a negative balance, the mitochondria are challenged. A challenged mitochondria will improve its function and abilities. 

The challenged mitochondria is better at biogenesis, energy production and other tasks. The unchallenged mitochondria fragments and fails; this is the heart of the NCD problem.

There is a profound effect on mitochondria by exercise. Sustained strenuous physical exercise can double the mitochondrial contents and activity. It will also increase the coupling of mitochondria and improve efficiency and function. 

One of the ways that enhance function of mitochondria during calorie restriction or exercise is the AMPK (AMP-activated protein kinase) path. AMPK is an energy sensor. This molecule is deacetylated during fasting or exercise by SIRT-1. Deacetylation of AMPK increases its activity. 

AMPK functions to sense energy imbalances in the cell and then to initiate cell protection. When the energy supply is low, the cell and organism will respond by slowing down aging and increasing protection from many age-related problems.

Providing antioxidants also improves mitochondrial function by allowing for excessive levels of ROS to be removed from the organelles and cells. Additionally, anti-inflammatory molecules also improve function by protecting the cell membranes and changing the environment of chronic inflammation to a more healthy one.

Less inflammation means less reactive oxygen species and less oxidative stress.

There must be harmony in the generation of mitochondrial components from the nuclear and mitochondrial genomes. This is achieved by the PPAR-gamma, SIRT1 and AMPK signalling pathway. There must be a balance between mitochondrial fusion and fission.

Fusion is the interconnection and enlargement of mitochondria to produce more energy. Fission is the repair/replace cycle for damaged mitochondria. For example, an abnormal accumulation of autophagy vacuoles from fission is a prominent feature of neurons in AD.

Defective oxidative phosphorylation in the mitochondria leads to excessive amounts of ROS and therefore elevation of oxidative stress. This causes more mitochondrial damage and a negative feedback loop happens. The role of antioxidants and anti-inflammatories is to stop this loop and to remove the unneeded ROS.

Many of our products are designed to help reduce inflammation. In particular, our Nervous System Multi is designed to improve neural health by optimizing mitochondrial function.

ABOUT THE AUTHOR

Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

Surgeon Formulated
For Your Peace of Mind

Natural Ingredients + Cutting-Edge Medical Breakthroughs.

100% NATURAL PAIN RELIEF FOR PEOPLE WORLDWIDE

What Are Inflammatory Markers, And Why You Should Check Them

What Are Inflammatory Markers, And Why You Should Check Them

Chronic inflammation is a type of slow, long-term and damaging inflammation that lasts for a prolonged period of time. It may last from several months, up to many years – and you may not be aware that you’re experiencing it. 

In the modern world, such low-grade inflammation starts in childhood and lasts until the end of life (generally speaking).

This type of inflammation is hard to discover. You likely won’t see swelling like you would around a cut or a bruise. Instead, you may simply feel sore, have achy muscles, or may feel fatigued. Most noncommunicable (you can’t ‘catch’ it) diseases are due to this phenomenon.

Keep reading to learn more about low-grade and chronic inflammation, what your inflammatory markers are, and how to get them tested: