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Natural Sources Of PEA

What Is PEA (Palmitoylethanolamide)?

PEA is a natural fatty acid compound that has been found in various clinical trials to modulate pain and mood receptors in your body’s natural regulatory, or endocannabinoid, system. This makes it a great modulator of pain, inflammation, and mood, regulating more balanced stress response.

Pain and inflammation are normal parts of your body’s recovery processes. If you injure yourself, the subsequent pain and inflammation protect the injury site to prevent further damage.

PEA works directly on PPAR receptors in your endocannabinoid system. These are a group of cellular receptors that are involved in your body’s pain and inflammatory pathways. Your body naturally produces PEA to help your body recover from pain and inflammation. Still, when your body doesn’t produce enough PEA, you can experience prolonged pain and inflammation that does more harm than good.

Other Sources Of PEA

PEA can be found in a variety of foods: It is located in egg yolks. The anti-inflammatory and immune-enhancing effects were discovered in 1939 during a study of underprivileged children; those who received PEA from egg yolks had no rheumatic fever recurrence despite repeated attacks of hemolytic strep infections. Soybeans, alfalfa, and peanuts are also excellent sources of PEA.

It’s also possible to supplement with PEA. We decided to include PEA in our Essential Multivitamin and topical creams for its potent anti-inflammatory, neuroprotective, and analgesic properties. We utilized micronized, and ultra micronized PEA to allow for better absorption.

The Essential Multivitamin reduces inflammation by giving you a high-potency source of vitamins and nutrients that are commonly missed in the modern diet. This enables your body to regulate its responses naturally – but we also added PEA to the formulation to give this multi an added boost.

Why You Should Supplement With PEA

Taking PEA to supplement your body’s shortage of essential healthy fatty acids and fatty acid products is a great way to regulate inflammation naturally. PEA is also neuroprotective, making it an excellent resource for controlling the symptoms of conditions such as diabetic neuropathy, sciatic pain, low-back pain, and other conditions such as multiple sclerosis. PEA has also been shown to support eye health.

There are no known adverse side effects of PEA supplementation. Even if you aren’t actively suffering from nerve pain – PEA is neuroprotective, which means that it can help protect your nervous system from future damage that occurs as you age. PEA generally reduces inflammation that is harmful while supporting helpful inflammatory responses against pathogens.

If you are currently taking medication for chronic pain or inflammatory disorder, PEA has been shown in some preliminary research to enhance the medication’s effect naturally. There are no known clinically significant interactions with medications.

You can also use PEA topically to relieve muscle, joint, and ligament pain at the application site. We formulated our new Pain Relief + Recovery Cream with PEA, Menthol, Turmeric, and other natural botanicals to both immediately cool and relieved topical pain and slowly melt away recurring inflammation over time. 


Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

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