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Why Does CBD Work so Well?

CBD and The Medical Field

CBD is the newest trend in the health and wellness community – and is even making waves in the medical community for its health benefits as well. From fighting insomnia to reducing stress, treating seizures, and reducing inflammation, CBD has become the most well-known natural remedy for a host of conditions.

Read more: Can CBD Cure Epilepsy?

Because of CBD’s proven medical applications, there are many clinical trials being conducted – or have recently been conducted – showing its successful applications for the treatment of problems associated with conditions including (but not limited to) anxiety, pain + inflammation in joints, Parkinson’s, and more with limited, if any, side effects. 

This means that CBD has the potential to be a safe and holistic alternative to heavy pharmaceutical treatments, which often have discouraging side effects.

How Does CBD Work?

You might be wondering how CBD can be successfully utilized to treat so many different conditions – and you aren’t alone. Most of the research being performed by the medical and scientific communities focuses on how CBD interacts with the body.

Their research has found that CBD mimics endocannabinoids, which are chemicals that your body produces naturally. CBD itself is a phytocannabinoid, as such, it is able to attach to receptors in your body to exert its therapeutic effects. The two receptors it is known to either regulate or attach to are CB1 and CB2 receptors.

CB1 receptors are found mostly in the brain and are related to things like coordination, pain, emotions, appetite, and more.

CB2 receptors are more commonly found in the immune system, and influence the body’s inflammatory response and signal pain receptors. When you stub your toe and the tissue surrounding it gets swollen and inflamed, that is inflammation. CB2 receptors are found on cells involved in inflammation and therefore phytocannabinoids can directly influence that inflammatory response.

CBD has been shown to interact with the receptors on certain white blood cells – which makes it possible, therefore, for CBD to naturally suppress the body’s inflammatory response and balance pain. CBD is also able to modulate certain nervous system neurotransmitters and thus regulate mood. 

These neurotransmitters are essential to your overall health and well-being, and when these neurotransmitters are “misfiring,” aka, promoting neural imbalance and inflammation, it can wreak havoc on the body. Overly elevated or diminished production of certain endocannabinoids create imbalance in other physiologic systems; this causes imbalances and symptoms such as pain,depression, lower immune function, and more.

How CBD Promotes Balance

mentally & physically

When ingested or used in topical formulations, Cannabidiol has the ability to naturally increase your body’s endocannabinoid levels, but in addition to that, it protects your receptors from being overly stimulated. It has been shown to bind to CB1 receptors in a different pattern than the cannabinoids your body produces on its own, reducing the receptor’s ability to allow other cannabinoids to bind to it, thereby reducing its responsiveness. 

This is a good thing, as most imbalances are caused by overactive receptors – causing things such as anxiety, appetite, and fluctuating weight. CB1 receptors are balanced themselves, by CB2 receptors.

CBD does more than just bind to or alter the function of CB1 and CB2 receptors, however. It has the ability to interact with other receptors, such as serotonin receptors in the brain, and pain receptors that respond to temperature and respond with a pain and heat sensation.

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CBD can mimic serotonin and bind affect receptors in the brain, activating them and playing a role in reducing anxiety, depression, and more. It can also bind to the receptors that sense injury, reducing your body’s inflammatory response and promoting a more gentle, and appropriate, reaction to injury. 

When you are injured, discomfort occurs from the injury itself, and the swelling, heat, and pain that the body produces following the injury. CBD’s ability to bind to these receptors, called TRVP1 receptors, is what makes it a prime candidate for treating epilepsy and reducing discomfort caused by arthritic joints.

How Does It Interact With Medications?

If you are considering using CBD to manage symptoms related to inflammation, emotional distress, and more, you may already be taking medications prescribed by your doctor. Even if you are not on other medications, it’s wise to consult with your physician before starting a CBD regimen. Your physician will likely be able to recommend trustworthy brands and products that are suited for your particular condition.

Because of its wide range of uses, cannabidiol is becoming increasingly utilized for its therapeutic properties. Much of the science surrounding how it exerts its effects is still being developed, but early findings all point to it being a remarkably risk-free alternative to more side effect-prone medications. 

While it should never be used instead of prescribed medication (unless your physician gives you the go-ahead,) it has been shown in dozens of early trials to effectively reduce inflammation, curb anxiety, and improve overall well-being.

Ready to try CBD for yourself? Look no further than Well Theory – a surgeon-curated line of holistic CBD products designed to improve your overall health with emphasis on reducing inflammation in the musculoskeletal system, and restoring balance. 



Dr. Meredith Warner is the creator of Well Theory and The Healing Sole. She is a board-certified Orthopedic Surgeon and Air Force Veteran.

She is on a mission to disrupt traditional medicine practices and promote betterment physically, spiritually and mentally to many more people. She advocates for wellness and functional health over big pharma so more people can age vibrantly with more function and less pain.

At Well Theory, Our surgeon-designed products are FDA Registered and formulated to help people:

  • Manage the symptoms of musculoskeletal pain
  • Recover vibrantly from orthopedic related surgeries
  • Fill the gaps in our daily diets
  • Manage pain associated with inflammation

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